Artivigil 150 mg – US To US

What is Artvigil 150mg?

Artvigil 150 mg is used to promote wakefulness in patients with narcolepsy, obstructive sleep apnea & shift work sleep disorder due to excessive daytime sleepiness. It works by affecting certain chemicals in the brain that deal with dopamine, norepinephrine, histamine, and orexin/hypocretin. Artvigil 150 mg is a generic version of Armodafinil 150mg sold under the name Nuvigil 150mg in the United States of America (USA).

The IUPAC name for provigil 100mg is (diphenylmethanesulfinyl) acetamide. Its chemical formula is  C15H15NO2S and its molecular weight is 273.35. Provigil is classified as BCS category II, which has low solubility and high permeability. It is primarily metabolised in the liver by the cytochrome P450 enzyme system, primarily the CYP3A4 and CYP2B6 enzymes. It  is moderately bound to plasma proteins, with approximately 60% to 63% binding. The half-life of Provigil 100mg is approximately 12 to 15 hours in most individuals

What are The Uses of Artvigil 150mg Tablets?

The main component of Artvigil 150 is armodafinil. Armodafinil is known for its wakefulness-promoting properties.  Some of the common uses are given below. Artvigil 150 mg (Armodafinil) in USA is used to treat excessive daytime sleepiness due to narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

• Artivigil can be effective for problems such as narcolepsy, sleep apnea, and shift work sleep disorder (SWSD).
• By using this medication, one can improve cognitive function, which includes attention, memory, and executive functions.
• For tasks that demand continual attention and concentration, Artvigil may assist individuals to remain focused and be productive.
• Artvigil is sometimes used off-label to treat conditions such as attention deficit hyperactivity disorder (ADHD), depression, and fatigue associated with various medical conditions.
• As an additional therapy for depression, some patients are recommended to take Artvigil 150 mg, where exhaustion and cognitive impairment are major symptoms
• Patients experiencing fatigue related to medical conditions such as multiple sclerosis, fibromyalgia, or chronic fatigue syndrome may find relief with Artvigil, as it can alleviate excessive daytime sleepiness and improve alertness.
• Another off label usage could be used to improve cognitive processes like memory, decision-making, and problem-solving.

What are The Dosage Guidelines for Artvigil 150mg Tablets?

The dosage guidelines for Artvigil 150mg tablets typically involve taking one tablet orally once a day in the morning. It is advisable to take Artvigil with or without food, according to individual preference. Dosage adjustments may be necessary based on individual response and tolerability, and they should be made under the guidance of a healthcare professional. It is essential to follow the prescribed dosage regimen and avoid exceeding the recommended dose without consulting a healthcare provider. Additionally, adherence to the prescribed dosage schedule helps maintain consistent drug levels in the body for optimal therapeutic effects.

How do I Take An Artvigil 150mg Tablet?

• Swallow the Artvigil 150mg tablet whole with a full glass of water.
• Take it orally in the morning, with or without food.
• Maintain consistent timing daily for optimal effectiveness.
• Avoid alcohol consumption and attend follow-up appointments regularly.

Missed Dosage Guidelines

• The missed dose should be skipped and the regular dosage should be resumed. 
• It’s important not to double up on doses to make up for a missed one, as this can increase the risk of adverse effects.

Overdosage Guidelines

• If someone has consumed more than the prescribed amount, they should seek medical assistance or contact a poison control centre.
• A provigil overdose can cause agitation, disorientation, hallucinations, a fast heartbeat, perspiration, nausea, vomiting, and seizures, among other symptoms. Must be closely supervised
• Should visit the nearest emergency services as soon as possible if a person has overdosed on the drug.
• Do not attempt to treat a Provigil overdose at home without medical supervision, as it can increase the risk of complications 
• Provide healthcare providers with information about the amount of Provigil ingested, the time of ingestion, and any other medications or substances taken concurrently.
• Keep Provigil out of the reach of minors and anyone else who might abuse or inadvertently consume the drug to avoid accidental overdosing.

How does Artvigil 150mg Tablet Work?

The mechanism of action is that it  has the ability to make you more awake.

Artvigil 150mg is a FDA approved prescription drug contains Armodafinil used for wakefulness in drowsy people with daytime sleepiness due to narcolepsy, obstructive sleep apnea & shift work sleep disorder. It works by changing the brain’s chemical systems, mostly those that deal with dopamine, norepinephrine, histamine, and orexin/hypocretin. 

Pharmacodynamics

• Provigil alters the release and absorption of neurotransmitters in key brain regions that regulate sleepiness, primarily dopamine and norepinephrine. Provigil increases the release of these substances and prevents their absorption, which increases alertness and awakeness.
• One neuropeptide that aids in preserving the sleep-wake cycle is orexin. Provigil makes you feel less drowsy and more awake by increasing the activity of orexin.
• Histamine is another type of chemical. Histaminergic neurotransmitters are molecules that help you stay alert, and Provigil increases their transmission

Pharmacokinetics

• Following oral treatment, provigil is quickly absorbed and reaches peak plasma concentrations in two to four hours.
• It is largely metabolised by the cytochrome P450 enzyme system in the liver, specifically CYP3A4 and CYP2B6.
• Provigil has an elimination half-life of roughly 12 to 15 hours. The majority of the drug is excreted from the body through urine, leaving only a small amount undisturbed. 

What are The Side Effects of Artvigil 150mg Tablets?

There are some side effects of Artvigil 150 mg tablets, such as 

• Periodic arrhythmias or palpitations may occur occasionally while taking Artvigil.
• Increased blood pressure, particularly in patients with preexisting hypertension, may occur.
• In very few cases, visual problems like blurred vision have been reported.
• Artvigil may make it hard to fall asleep or stay asleep, especially if taken later in the day.

Also, headache, nausea, anxiety, nervousness, dry mouth, and dizziness are some more side effects of Artvigil 150 mg.

There are some serious side effects too, such as.

Severe Allergic Reactions

Severe allergic reactions such as angioedema and anaphylaxis are extremely uncommon in Provigil users. Some of the side effects include a rash, breathing difficulties, and swelling of the face, lips, tongue, or throat. 

Effects on Psychiatric Conditions

Provigil may exacerbate or cause the emergence of mental health conditions such as anxiety, agitation, hallucinations, or suicidal thoughts. Those who use Provigil should be closely watched for any changes in their behaviour or emotions.

Cardiovascular Effects

Blood pressure and heart rate may rise while taking Provigil, especially in people who are prone to cardiac problems. If you take heart medicine in addition to Provigil, you should be cautious and have your blood pressure checked.

Problems with the Liver

Users of Provigil have developed hepatocellular necrosis and other serious liver damage. Individuals who have liver disease should be closely monitored for symptoms such as elevated liver enzymes, stomach pain, or jaundice.

Seizures

Rare but  Artvigil 150 mg may raise the chance of seizures, especially in people who already have epilepsy or are predisposed to having seizures.

Precautions & Warnings:

• A healthcare provider should be consulted before using the wakefulness-promoting medication Artvigil 150mg. 
• It is very important to think about how this drug might interact with other drugs, any physical illnesses that you may already have, and any history of drug abuse or mental health problems. 
• Without a doctor’s consent, people who are pregnant or nursing should not use Artvigil.
• As patients adapt to Artvigil, they should be aware of possible side effects. It’s crucial for them to avoid tasks requiring high mental focus until they understand how the medication affects them. This precaution ensures their safety and the safety of others in activities that need undivided attention. 
• Furthermore, patients should limit alcohol consumption while on Artvigil, as it may intensify side effects. Those with allergies to Artvigil’s components should avoid using it.
• To ensure safe and effective use, follow healthcare professionals’ instructions and monitor for adverse effects. This approach promotes both the patient’s well-being and the medication’s intended purpose.

Interactions:

Artvigil interacts with various medications and factors. 

• It may reduce the effectiveness of hormonal contraceptives and should prompt users to consider additional contraception. 
• Some antifungal drugs can inhibit Artvigil metabolism, increasing blood levels and risk. 
• CYP3A4 inducers/inhibitors can alter Artvigil levels, affecting its efficacy or side effects. 
• Combining Artvigil with CNS depressants, psychiatric medications, or cardiovascular drugs may cause complications. 
• Smoking tobacco can reduce Artvigil’s efficacy, and food may delay its absorption. 

To ensure safe and effective use, patients should inform their healthcare providers about these interactions and follow recommended guidelines.

FAQs:

Q. What is Artvigil 150mg used for?

Artvigil 150mg is primarily used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

Q. What are the common side effects of Artvigil 150mg?

Common side effects of Artvigil 150mg may include headaches, nausea, dizziness, dry mouth, and insomnia. These side effects are usually mild and temporary

Q. How should I take Artvigil 150mg?

Artvigil 150mg tablets should be taken orally once a day in the morning with or without food to improve wakefulness. Avoid taking it late in the day to prevent insomnia.

Q. Is Artvigil 150 mg safe during pregnancy and breastfeeding?

The safety of Artvigil 150mg during pregnancy and breastfeeding is not well established. Consult a healthcare provider before using Artvigil if you are pregnant or nursing

Q. Can I drink alcohol while taking Artvigil 150mg?

It is advisable to avoid or limit alcohol consumption while taking Artvigil 150mg, as alcohol may increase the risk of side effects and impair judgement and cognitive function.

Q. Is Artvigil 150 mg habit-forming?

Artvigil 150mg has the potential for abuse and dependence, particularly in individuals with a history of substance abuse or addiction. Use it carefully and only as directed by a medical professional.